Rheumatoid arthritis is a chronic autoimmune inflammatory disease of the young woman. Dr. Mobeen Syed explains that the patient develops IgG and IgM against the Fc portion of the IgG( normal IgG in the patient). These are called RA factors. RA factors are the autoantibodies produced against normal antibodies.
During the active period of the disease, the RA factor increases, and complement reduces because of complement fixation, which causes hypocomplementemia and increased inflammation.
Dr. Mobeen Syed describes that glomerulonephritis, rheumatoid arthritis, SLE, polyarteritis nodosa, and allergic lung diseases occur due to type III hypersensitivity reactions.
Rheumatoid arthritis attacks joints, pericardium, and lungs.
Systemic lupus erythematosus is also a chronic, inflammatory autoimmune disease in the woman, but it occurs in the skin of the face, joints, and kidney.
In systemic lupus erythematosus, antibodies are anti-DNA antibodies, not the auto-antibodies.
The following topics have discussed:
* Definition of rheumatoid arthritis
* Major attack sites of rheumatoid arthritis
* RA factors
* Definition of SLE
* Site of action of SLE
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